Overview

	SLIDEVIEW VS200 Universal Slide Scanner Multimodal imaging for advanced research and specialized digital pathology. The SLIDEVIEW™ VS200 system is designed to capture a wide variety of samples and stains with multiple magnifications, flexible slide sizes, and up to 10 imaging modes from brightfield to fluorescence. High-resolution imaging of whole slides empowers your lab to unlock more insights from your samples. Get in Touch

SLIDEVIEW VS200 Universal Slide Scanner

Multimodal imaging for advanced research and specialized digital pathology.

The SLIDEVIEW™ VS200 system is designed to capture a wide variety of samples and stains with multiple magnifications, flexible slide sizes, and up to 10 imaging modes from brightfield to fluorescence. High-resolution imaging of whole slides empowers your lab to unlock more insights from your samples.

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Choose Your Application

SLIDEVIEW VS200

SLIDEVIEW VS200 for Life Science Research

The SLIDEVIEW VS200 system offers high-resolution slide scanning for advanced research applications, such as neuroscience, cancer and stem cell research, and spatial biology. With the flexibility of up to 10 imaging modes, multiplexing capabilities, and multiple magnifications up to 100X, the system delivers outstanding image quality for quantitative analysis.

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SLIDEVIEW VS200 for Digital Pathology

As a flexible yet intuitive scanner, the SLIDEVIEW VS200 system enables your team to digitize a wide range of sample types with minimal training. The VS200 system helps you achieve a fully digital workflow for pathology with versatile slide scanning, outstanding image quality, and flexible integration options. Get the evidence you trust for standard and specialty samples to make breakthrough decisions with confidence.

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Key Benefits

Confidence in Your Data Quality

Advanced optical innovation and automation make high-quality imaging routine and reproducible, reducing setup, variability, and user dependence across experiments and users.

Smarter Imaging and Workflow

Accelerate your path from slide to results with an intuitive interface, enhanced batch-scanning capabilities, faster workflows, and AI-based segmentation tools. Reduce human error, manual effort, and have more confidence in your results.

^{Colon stained with Masson’s trichrome.

Image data courtesy of Wenjin Chen, Rutgers Cancer Institute of New Jersey.}

Centralized Image Access

Managing the large amount of data generated by a slide scanner is easier than ever thanks to our Net Image Server (NIS) SQL database and OlyVIA™ web programs. Scan and automatically upload your images to one or more databases, differentiate between users, and take advantage of offline visualization and annotation tools.

Specifications

SPECIFICATIONS		VS200 Single Tray	VS200 Multiple Tray Loader
Intended Specimen	Observable Specimen	Glass slide with cover glass and without cover glass^*1
	Size of Glass Slide (W × L × H)	Standard slide tray: 25 mm–26.5 mm × 75 mm–76.5 mm × 0.9 mm–1.2 mm (1 in. × 3 in. × 0.05 in.) (6 slides) Optional trays: 1) 47 mm–50 mm × 27 mm–30 mm × 1.2 mm–1.6 mm (1 in. × 2 in. × 0.05 in.) (3 slides) 2) 51 mm–53 mm × 75 mm–76.5 mm × 0.9 mm–1.2 mm (2 in. × 3 in. × 0.05 in.) (3 slides) 3) 75 mm–76.5 mm × 100 mm–102 mm × 0.9 mm–1.2 mm (3 in. × 4 in. × 0.05 in.) (1 slide) 4) 100 mm–102 mm × 126 mm–128 mm × 1.1 mm–1.4 mm (4 in. × 5 in. × 0.06 in.) (1 slide)
	Cover Glass Thickness	0.12–0.17 mm
	Observation Methods	Brightfield, brightfield mono, reflected brightfield (optional²), darkfield, phase contrast (optional^3), linear polarization (optional^*4), circular polarization (optional), DIC (optional), fluorescence (optional), fluorescence optical sectioning with speckle illumination (optional VS-SILA module)
Optical Frame	Illuminator	Built-in Köhler illumination for transmitted light; high intensity and high color rendering LED (up to 50,000 hours)
	Objectives	2X, 4X^5, 10X^5, 20X, 40X^5 60X^5, and 100X^*5 compatible objectives for a 6-position motorized nosepiece (including selected oil immersion, silicon oil immersion, and phase contrast objectives) Optional automatic liquid dispenser
	Motorized Stage	XY stage with automatic control
	Focusing	Motorized focusing with automatic control
	Color Camera	Integrated 2/3 inch CMOS, 3.45 μm × 3.45 μm pixel size, high sensitivity, high resolution
Scan Unit	Capacity	1 slide tray, 6 slides maximum; upgradable to a multiple tray loader model	Up to 35 slide trays, 210 slides maximum
	Pixel Resolution (Color Camera)	Color camera UPLXAPO20X (NA 0.8): 0.274 μm/pixel Options: UPLXAPO4X (NA 0.16): 1.37 μm/pixel UPLXAPO10X (NA 0.4): 0.548 μm/pixel UPLXAPO40X (NA 0.95): 0.137 μm/pixel UPLXAPO40XO (NA 1.4): 0.137 μm/pixel UPLXAPO60XO (NA 1.42): 0.091 μm/pixel UPLXAPO100XO (NA 1.45): 0.055 μm/pixel Up to 35 slide trays, 210 slides maximum Monochrome camera Hamamatsu Orca camera UPLXAPO4x (NA 0.16) 1.625 μm/pixel UPLXAPO10X (NA 0.40) 0.650 μm/pixel UPLXAPO 40X (NA 0.95) 0.163 μm/pixel UPLXAPO40XO (NA 1.4) 0.163 μm/pixel UPLXAPO60XO (NA 1.42) 0.108 μm/pixel UPLXAPO100XO (NA 1.45) 0.065 μm/pixel
	Scan Time	Brightfield: approx. 1.5 minutes (20x objective, scan area 15 mm × 15 mm) Fluorescence widefield NOVEM: approx. 14 minutes (20X objective, scan area 15 mm × 15 mm, 4 channels, 50 ms exposure each)
	Software	Automatic sample detection (generic and TruAI deep learning), automatic barcode reading, automatic focus mapping, automatic scanning, automatic stitching, pause and resume scanning, Z-stack imaging, extended focus imaging (EFI), image format: VSI, JPEG, TIFF, DICOM, synchronized multi-image display, stepless zooming, zooming while scanning, annotations, screen capture, slide loader control (multiple tray loader only)
Fluorescence (optional)	Fluorescence Components	UPLFLN4X objective (recommended for overviews), illuminator with fly-eye lens, motorized mirror turret, motorized filter wheel Widefield light source options: U-LGPS, Excelitas X-Cite XYLIS-2, X-Cite NOVEM, KL2500LED, CoolLED pE-10 VS-SILA: up to 6-line laser combiner and scrambler unit
Fluorescence (optional)	Monochrome Camera	Options: VS-304M (12-bit), 1-inch CMOS, 3.45 μm × 3.45 μm pixel size (12MP) HAMAMATSU ORCA Flash (16- bit)4.0 V3 HAMAMATSU ORCA Fusion (16- bit) HAMAMATSU ORCA Fusion BT (16- bit)
Solutions for Scanner Software (optional)	Solution License	Batch image format converter DICOM converter fluorescence VS-SILA acquisition Net Image Server (NIS) SQL
Desktop Software (optional, separate solution for analysis)	Solution License	Batch image format converter DICOM converter Detection and analysis Deep learning 3D deconvolution
Environment	Weight	Optical frame: 75 kg (165.3 lb) 1 slide tray: 0.6 kg (1.3 lb)	Optical frame and multiple tray loader: 149 kg (328.4 lb) 35 slide trays: 21 kg (46.3 lb)
	Weight	Fluorescence: 8 kg (17.6 lb) PC and monitor: 19 kg (41.9 lb) Camera cover (optional): 9 kg (19.8 lb)
	Operating Environment	Computer and monitor: 19 kg (41.9 lb) Camera cover (optional): 9 kg (19.8 lb)
	Operating Environment	Temperature: 15–28 °C (59–82.4 °F) (including other devices) Humidity: up to 80% (31 °C (87.8 °F))
	Power Consumption	221 W
	Power Supply*⁵	Input: 100–240 V AC; 50/60 Hz; 4 A Output: 24 V DC, 9.2 A
Software Integration	Compatible Analysis Software	Visiopharm, Indica Labs, Andor/Imaris, Fiji, QuPath, Media Cybernetics, Applied Spectral Imaging, Proscia, Inspirata, Corista, MindPeak, Patholytix, HistoMetrix

^*1 Optional phase contrast objectives are required.
^*2 Optional light source, illuminator, motorized mirror turret, and mirror unit are required.
^*3 Optional phase contrast objectives are required
^*4 Optional analyzer mirror unit and motorized mirror turret or manual rotatable analyzer are required.
^*5 Sold separately

Release Note

Version 5.1

New Hardware Support

CoolLED pE-10
CoolLED pE-800
1×2 inch tray

New Functions and Improvements

Refreshed user interface with new icons and vertical and horizontal tabs for easier navigation
Able to search for scan projects
Multiple detail scans in one workflow, new multi-scan project type
AI sample detection during the first detail scan
AF results in overview images are used in batch mode
Manual focus allowed in batch scans, with recorded focus positions
After finishing a batch scan, any of the slides can be selected and rescanned
Added the option of channel by channel acquisition and alignment (regular and multiplex)
Pseudocolor of FL observation methods can be set in the scan wizard
Software algorithm improved for multiplexing alignment
Any transmission channel can be visualized alongside FL channels in the tile view
Image remains rotated after re-opening it in the software
Software reminder for liquid dispenser maintenance
Microsoft Entra ID (MFA authentication) can be used for authentication for Net Image Server, in addition to SQL and Windows accounts
Annotations made in the OlyVIA web viewer can be visualized in OlyVIA Desktop

Version 4.3 (IVD)

VS200 ASW software version 4.3 is used to control the SLIDEVIEW DX VS200 slide scanner, a CE-marked device under the EU IVDR for use in clinical diagnostics in Europe. This software is based on the research use only (RUO) software, version 4.2.

Differences Compared to Version 4.2

Additional page and links in the disclaimer, home page, and online help explaining the IVD compatible software functions
No database functionality

Notes About Licensing

RUO and IVD licenses are not connected; Scanners with RUO software cannot be updated to an IVD version, and vice versa
VS200 Desktop and OlyVIA Desktop are RUO and not IVD certified

Version 4.2

New Hardware Support

Supports up to six wavelengths for VS-SILA acquisition, with a wider wavelength range from 395 to 785 nm
U-LGPS type 2, possible to control individual wavelength on/off and power
New polarization angle changer (rev2)
Calibration slide with no coverslip supporting all no coverslip objectives

New Functions and Improvements

Automatic Z-range measurement
Deep learning update (image regression, simplified labeling, instant training, new pretrained IHC network from cellSens 4.2) in VS200 Desktop
Object counting in VS200 Desktop
Export image dialog (from cellSens 4.2) are added to all VS200 software
NIS can be installed on virtual machines in a cloud environment (we tested Microsoft Azure) with certain limitations
Magnification is saved as a DICOM tag
More clinical related fields can be saved directly as DICOM tags
Label orientation in DICOM is adjusted to better match available PACS
New video tutorials: scanning with virtual Z, improving sample detection, optimizing autofocus are added to the online help of VS200 ASW software

Version 4.1.2

New Functions and Improvements

Cybersecurity update: CodeMeter is updated to v7.60d
Optimization of NIS SQL and OlyVIA web to support more clients
OIR format is supported as an input format in VS-CONV solution

Version 4.1.1

New Hardware Support

Laser combiner (405, 488, 561, 638 nm wavelength) for VS-SILA acquisition
U-LGPS white LED
KL-2500 for reflected brightfield
Optical sectioning device and trigger board for VS-SILA acquisition

New Functions and Improvements

VS-SILA module for optical sectioning
VS200 ASW, NIS SQL, VS200 Desktop, and OlyVIA Desktop support in Windows 11
Additional image layers (sample masks, focus point, focus map, and sharpness layer) can be optionally created during image acquisition
Integration of credential manager for the NIS SQL database
Top and bottom: defining absolute Z-range in live for virtual Z acquisition
Pre-processing of DICOM fluorescence scan to optimize the 8-bit only display of DICOM viewers
Support of converting OIR file format to DICOM
Save and load ROIs functionality
Support for the MicroPDF417 barcode type
Images can be downloaded from OlyVIA web