Overview

	Discover More, Faster Than Ever Experience exceptional speed, clarity, and reliability with the IXplore™ IX85 Pro. With an industry-leading 26.5mm field number (FN), combined with new advanced imaging tools that ensure clear, accurate results, the IXplore IX85 Pro system empowers you to capture more data and uncover insights faster than ever before.

Discover More,
Faster Than Ever

Experience exceptional speed, clarity, and reliability with the IXplore™ IX85 Pro.

With an industry-leading 26.5mm field number (FN), combined with new advanced imaging tools that ensure clear, accurate results, the IXplore IX85 Pro system empowers you to capture more data and uncover insights faster than ever before.

Comparison of how many cells you can acquire in different FN.

Expand Your View, Enhance Your Vision

See and capture more—and reduce your acquisition times—with an unmatched field of view (FOV) in the industry and an array of advanced end-to-end imaging features that set a new standard in clarity and precision, including groundbreaking new objective technology

Unmatched 26.5mm FOV

View more of your sample in each image with an industry-leading field number (FN) of 26.5mm on two integrated ports. Cover larger areas in fewer images, get more data in each image, minimize the need for image stitching, and speed up your workflows.

Edge-to-Edge Clarity Precision

Collect large, uniform images with higher-power LED illumination and built-in optics that provide you with consistent lighting across the entire FOV—essential for large-area imaging. Count on edge-to-edge precision with proprietary distortion correction technology and expanded flatness. Automatically create seamless, high-quality stitched images with intelligent shading correction.

2x3 stitched DIC image of cultured NIH 3T3 cells.
Left: Raw stitching, Right: Intelligent Shading Correction applied stitching. Sample provided by EnCor Biotechnology Inc.

Brain slice stitching with Intelligent Shading Correction
Cyan: nuclei, Green: microtubule associated proteins (MAPs), Magenta: Myelin Basic Protein (MBP)
Sample provided by EnCor Biotechnology Inc.
Left: Original stitching, Right: Intelligent Shading Correction applied stiching

A New Standard in Image Depth Objective Usability with Our New Multi-Immersion Objective

Introducing our new multi-immersion objective (LUPLAPO25XS) with groundbreaking new immersion technology. See deeper into your samples and reveal structures that were previously out of reach with a high NA and long working distance.

With silicone gel pad technology, you can get the quality of silicone immersion with the useability of a dry objective. There’s no need to wipe or replace oil as you navigate across the sample, there’s no risk of your immersion medium drying out during timelapse, and you can painlessly switch between air and immersion objectives.

The new LUPLAPO25XS enhances workflows for organoids, 3D cell culture, well-plates, and a wide range of applications, with crystal-clear imaging and no compromise in usability.

XYZ image comparison between Left: LUPLAPO25XS (Silicone gel) and Right: UPLXAPO20X (Dry)
Cleared HeLa*1 cell spheroid (Cyan: Nuclei, Magenta: Microtubules) taken by IX85-Spin

Exceptional Objective Performance

Unlock the full potential of our X Line™ high-performance objectives and silicone immersion objectives and get exceptional performance from our high-resolution/NA objectives together with our A Line applications-driven objectives.

With the power of the IXplore IX85 Pro, now you can combine a wider FOV, expanded flatness, and higher NA to create brighter, higher-resolution images with greater uniformity. Take full advantage of this power to obtain excellent quality with minimal phototoxicity and/or photobleaching, and achieve exceptional color reproducibility during brightfield and multicolor fluorescence imaging.

Stunning 3D Images

Use TruSight technology to create 3D images with confocal-like sharpness at the speed of a widefield microscope, and explore 3D samples in real time with advanced software solutions that help you see more and see it faster.

Learn More About TruSight Technology

Optimize Your Workflow,
Accelerate New Discoveries

No matter the size of your lab, make getting your best image simpler with a new automated objective correction system, customizable interfaces, efficient task management software, and advanced real-time image processing and analysis.

New Automatic Correction Collar

Our new correction collar automatically fine-tunes your objective settings and optimizes image quality by reducing spherical aberrations caused by variations in cover glass thickness. Create sharper, more detailed images and eliminate time-consuming manual adjustments with the simple click of a button. Compatible with over 18 different objectives to meet your research needs.

Advanced Real-Time Image Acquisition Analysis

When combined with industry-leading FN and FOV, the IXplore IX85’s advanced imaging tools provide you with consistent, accurate, crystal-clear results. Quickly locate samples and acquire high-magnification images. Automatically analyze key features in your images. Easily manage multidimensional tasks, including 5D experiments.

One Platform, Infinite Possibilities Stay at the forefront of technology with the IXplore IX85 Pro’s unmatched customizability. Now you can support diverse imaging modalities across a variety of applications with no sacrifice in performance—and empower your lab to stay prepared for whatever the future brings.
	New Built-In Ports Two built-in camera ports (left and right) and an optional third port enable enhanced functionality and the capacity to create a multi-camera configuration setup. Four optical paths are available: left (100%), right (100%), binocular (100%), and BI 50%/L 50%.
Versatile Deck Structure Customize your microscope setup for your own experiments. An open frame design makes it simple to add or swap modules to customize functions as needed. You can also upgrade from one to two decks as research needs change.
	New Built-In Threaded Holes Built into the frame, threaded holes around the camera ports turn the IXplore IX85 Pro into a canvas for innovation, whether you’re building a custom system or integrating the frame into your product.
Modular System Design Leverage the latest technology with a modular system that lets you upgrade and expand your platform as research needs evolve by adding features such as TruFocus™, environmental control, and imaging modalities like Spinning Disk, TIRF, photomanipulation, and SMLM. Third-party compatibility supports top-tier incubation systems, motorized stages, and more.
Live	TIRF	Spin
*1 Although it became one of the most important cell lines in medical research, it’s imperative that we recognize Henrietta Lacks’ contribution to science happened without her consent. This injustice, while leading to key discoveries in immunology, infectious disease, and cancer, also raised important conversations about privacy, ethics, and consent in medicine. To learn more about the life of Henrietta Lacks and her contribution to modern medicine, click here. http://henriettalacksfoundation.org/

One Platform, Infinite Possibilities

Stay at the forefront of technology with the IXplore IX85 Pro’s unmatched customizability. Now you can support diverse imaging modalities across a variety of applications with no sacrifice in performance—and empower your lab to stay prepared for whatever the future brings.

New Built-In Ports

Two built-in camera ports (left and right) and an optional third port enable enhanced functionality and the capacity to create a multi-camera configuration setup. Four optical paths are available: left (100%), right (100%), binocular (100%), and BI 50%/L 50%.

Versatile Deck Structure

Customize your microscope setup for your own experiments. An open frame design makes it simple to add or swap modules to customize functions as needed. You can also upgrade from one to two decks as research needs change.

New Built-In Threaded Holes

Built into the frame, threaded holes around the camera ports turn the IXplore IX85 Pro into a canvas for innovation, whether you’re building a custom system or integrating the frame into your product.

Modular System Design

Leverage the latest technology with a modular system that lets you upgrade and expand your platform as research needs evolve by adding features such as TruFocus™, environmental control, and imaging modalities like Spinning Disk, TIRF, photomanipulation, and SMLM. Third-party compatibility supports top-tier incubation systems, motorized stages, and more.

Live

TIRF

Spin

*1 Although it became one of the most important cell lines in medical research, it’s imperative that we recognize Henrietta Lacks’ contribution to science happened without her consent. This injustice, while leading to key discoveries in immunology, infectious disease, and cancer, also raised important conversations about privacy, ethics, and consent in medicine.
To learn more about the life of Henrietta Lacks and her contribution to modern medicine, click here.
http://henriettalacksfoundation.org/

IXplore Microscopes

IXplore™ IX85

The IXplore™ IX85 platform delivers an unmatched level of customizability, allowing you to design or build an intelligent, high-performance imaging system that meets your specific goals. And with an industry-leading field number (FN) of 26.5mm plus an array of advanced end-to-end imaging and workflow features, the IXplore™ IX85 means you can capture more than ever before while dramatically reducing your acquisition times.

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IXplore™ IX85 Live

Designed to reduce photobleaching and phototoxicity, the IXplore™ IX85 Live system is optimized for physiological experiments involving live cell and tissue observation. Offering precise environmental control and enhanced rigidity, it supports long-term cell viability and stability for time-lapse imaging applications, such as in cancer, stem cell, and brain research.

Maintain focus accurately and reliably in time-lapse experiments with TruFocus™ Z-drift compensation system
Discover the real morphology of your cells with Olympus silicone immersion optics

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IXplore™ IX85 Pro

The foundation of our IXplore™ IX85 Pro system, the IXplore™ IX85 delivers an industry leading FOV and an array of advanced end-to-end imaging features, allowing you to see and capture more than ever before while dramatically reducing acquisition times. Experience exceptional speed, clarity, and reliability with the IXplore™ IX85 microscope system.

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IXplore™ IX85 Spin

The IXplore™ IX85 Spin system features a spinning disk confocal unit that enables fast 3D image acquisition, a large field of view, and prolonged cell viability in time-lapse experiments. Researchers can use it to perform rapid 3D confocal imaging with high resolution and contrast at greater depths for imaging into thicker samples. The spinning disk also helps to cut down on photobleaching and phototoxicity of samples upon excitation.

TruFocus™ Z-drift compensation system maintains focus for each frame
Precise 3D imaging with improved light collection using X Line™ objectives

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Specifications

		IX85P1ZF	IX85P2ZF
Microscope frame	Optical system	UIS2 optical system
	Revolving nosepiece	Motorized 6-position revolving nosepiece (DIC slider attachable), One position for Automated Correction Collar Simple water proof structure
	Focus	Stroke: 10.5 mm Minimum increment: 0.01 um, Maximum nosepiece movement speed: 3mm/s
	Intermediate Magnification Changer	3 positions (Coded) 1X / 1.6X / 2X
	Light path selection	Motorized 4 positions Eyepiece 100%, left 100%, right 100%, eyepiece 50%/left 50%
	Deck insert layer	1 layer	2 layers
	Maximum port field number	Left/Right side port: FN26.5, BI port: FN22 Deck right side port: FN18	Left/Right side port: FN18, BI port: FN22 Deck right side port: FN18
Focus compensator	TruFocus Z drift compensator	Offset method (Focus search, one-shot focus, continuous focus), Class 1 laser product, laser wavelength: 830nm
Transmitted light illuminator		Pillar tilt mechanism (30 ° inclination angle, with vibration reducing mechanism), Condenser holder (with with 88 mm stroke, refocusing mechanism), Field iris diaphragm adjustable, 4 filter holders Light source: High power LED light source
Observation tube	Widefiled (FN22)	• U-TBI90BK Wide field tilting binocular • U-BI90 Wide field binocular • U-TR30-2/U-TR30NIR Wide field trinocular
Stage	Motorized stage	• IX5-SSA: Stage stroke: X: 116mm x Y: 78mm, maximum stage movement speed: 40mm/s, Knob controller • 3rd party motorized stage
	Mechanical stage with right handle Mechanical stage with left handle	Stage stroke: X: 116mm x Y: 78mm, stage position locking function
	Right handle stage	Stage stroke: X: 50mm x Y: 50mm
	Gliding stage	Upper circular stage 360 ° rotatable, 20 mm (X/Y) travel
	Plain stage	232 mm (X) x 240 mm (Y) stage size, stage insert plate exchangeable (ø110 mm)
Condenser	Motorized long working distance condenser	W.D. 27 mm, NA 0.55, motorized turret with 7 position slots for optical devices (3 positions for ø30 mm and 4 positions for ø38 mm), motorized aperture and polarizer
	Long working distance universal condenser	NA 0.55, W.D. 27 mm 5 positions for optical devices (3 positions for ø30 mm and 2 position for ø38 mm)
	Ultra long working distance	NA 0.3, W.D. 73.3 mm, 4 positions for optical devices (for ø29 mm)
Fluorescence illuminator	L-shape-fluorescence illuminator	L-shaped design with exchangeable FS and AS modules, slider shutter and ND filter poket
Fluorescence mirror turret	Motorized fluorescence mirror turret	Motorized turret with 8 positions, built-in shutter, simple waterproof structurer
Fluorescence light source		• U-LGPS: LED and LDP light source, Class 1 laser product • 3rd party LED light source
Control unit (IX5-MCZ)		Nosepiece position, light path selection, filter turret position, FL shutter ON/OFF, DIA LED power, DIA LED ON/OFF, 4 customizable button
Control box (IX5-CBH)	PC interface	USB (Type-C), RS-232C
Operating enviornment	• Indoor use • Ambient temperature: 5 ºto 40 ºC (41 º to 104 ºF) • Maximum relative humidity: 80% for temperatures up to 31 ºC (88 ºF), decreasing linearly through 70% at 34 ºC (93 ºF), 60% at 37 º C (99 ºF), to 50% relative humidity at 40 ºC (104 ºF) • Supply voltage fluctuations: Not to exceed ±10% of the normal voltage

Resources

Manuals

IX85 Manual

IXplore IX85 Pro

Overview

Discover More,
Faster Than Ever

Expand Your View, Enhance Your Vision

Optimize Your Workflow,
Accelerate New Discoveries

One Platform, Infinite Possibilities

Live

TIRF

Spin